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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBA1
All Species:
30.61
Human Site:
S222
Identified Species:
67.33
UniProt:
P22314
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22314
NP_003325.2
1058
117849
S222
Q
P
L
S
A
M
V
S
M
V
T
K
D
N
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092142
1058
117902
S222
Q
P
L
S
A
M
V
S
M
V
T
K
D
N
P
Dog
Lupus familis
XP_538014
1015
112483
S222
Q
P
L
S
A
M
V
S
M
V
T
K
D
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q02053
1058
117790
S222
Q
P
L
S
A
M
V
S
M
V
T
K
D
N
P
Rat
Rattus norvegicus
Q5U300
1058
117769
S222
Q
P
L
S
A
M
V
S
M
V
T
K
D
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080185
1059
117949
S221
Q
P
L
S
A
M
I
S
M
I
T
K
D
N
P
Zebra Danio
Brachydanio rerio
NP_998227
1058
118200
S222
Q
P
L
S
A
M
I
S
M
I
T
K
D
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477310
1191
130740
A367
Q
P
I
S
T
M
I
A
S
I
T
H
D
A
Q
Honey Bee
Apis mellifera
XP_394434
1049
117087
A221
P
P
V
S
A
M
V
A
S
I
S
Q
D
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795302
1054
117556
S219
E
P
M
S
V
M
V
S
A
V
S
K
D
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22515
1024
114248
L227
D
K
L
N
D
G
T
L
F
K
V
E
V
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
90.2
N.A.
95.5
96.4
N.A.
N.A.
N.A.
77.6
78.8
N.A.
54.1
62.2
N.A.
65.2
Protein Similarity:
100
N.A.
99
92.1
N.A.
97.5
98.1
N.A.
N.A.
N.A.
90.1
90
N.A.
67.3
76.9
N.A.
80.7
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
86.6
73.3
N.A.
40
40
N.A.
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
93.3
N.A.
66.6
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
70.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
73
0
0
19
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
0
0
91
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
10
0
0
0
28
0
0
37
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
10
0
73
0
0
0
% K
% Leu:
0
0
73
0
0
0
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
10
0
0
91
0
0
64
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
46
0
% N
% Pro:
10
91
0
0
0
0
0
0
0
0
0
0
0
0
55
% P
% Gln:
73
0
0
0
0
0
0
0
0
0
0
10
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
91
0
0
0
73
19
0
19
0
0
19
0
% S
% Thr:
0
0
0
0
10
0
10
0
0
0
73
0
0
10
0
% T
% Val:
0
0
10
0
10
0
64
0
0
55
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _